WebJul 13, 2024 · This activity is usually mediated by telomeres, but in the nematode Caenorhabditis elegans special chromosome regions called “Pairing Centers” (PCs) have acquired this meiotic function. Through a genetic screen for mutations that cause meiotic nondisjunction, we discovered an uncharacterized meiosis-specific NE protein, MJL-1 … WebJan 1, 2012 · It is important to note that pairing centers are not unique to C. elegans. Both Drosophila males and budding yeast have cis-acting regions that promote chromosome pairing as well. Repetitive sequences in the rDNA are required for sex chromosome pairing in Drosophila males (McKee 1996).
Chromosome movement in meiosis I prophase Caenorhabditis …
WebDec 16, 2005 · We have investigated the role of pairing centers (PCs), cis-acting sites required for accurate segregation of homologous chromosomes during meiosis in C. … WebLoss of plk-2 results in defects in meiotic chromosome pairing and synapsis. Mutation of C. elegans plk-1, which encodes an ortholog of mammalian Plk1, results in inviability due to … forshaw richmond solicitors warrington
Targeting Polo-like kinase in space and time during C. elegans …
WebMar 6, 2007 · Despite this hiccup, the C. elegans story is surprisingly neat and tidy in comparison to what we know about most other organisms, where pairing and synapsis can seem too complicated to follow.C. elegans has adopted a simple and elegant mechanism for pairing and synapsis: do all or most of your pairing in one place; and maybe give that … WebJun 1, 2013 · Section snippets Regulation of meiotic chromosome dynamics at the pairing centers. A prerequisite for crossovers (COs) in C. elegans is the process of homologous pairing and synapsis [6, 7, 8]. Within the first few hours of meiotic prophase, each chromosome normally finds its partner. WebMar 13, 2009 · Author Summary C. elegans is a model system for diverse fields of biology, but its ability to serve as a model for quantitative trait gene mapping depends on its recombination rate in the laboratory and in nature. The latter is a function of how worms mate and migrate in the wild. We examined the patterns of recombination in a population … forshaw plumbing wirral