WebWe have identified two regions of the mouse gonadotropin-releasing hormone (GnRH) promoter, one between −237 and −201 (distal element) and the other between −184 and −150 (proximal element), which are required for glucocorticoid repression in transiently transfected GT1-7 cells. These sequences show no similarity to known positive or … Gonadotropin-releasing hormone (GnRH) is a releasing hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is a tropic peptide hormone synthesized and released from GnRH neurons within the hypothalamus. The peptide belongs to gonadotropin-releasing hormone family. It constitutes the initial step in the hyp…
Suppression of GnRH gene expression in GT1‐1 hypothalamic …
WebApr 28, 2011 · Because transcriptional regulation is crucial for the spatial and temporal expression of the GnRH gene, a region approximately 3.0 kb upstream of the mammalian GnRH promoter has been extensive ... WebNov 10, 1997 · The results suggest that both activation and inhibition of PKC decrease the GnRH gene expression in the GT1-1 cells probably through different signal cascade mechanisms. WE attempted to elucidate molecular mechanisms of gonadotropin-releasing hormone (GnRH) gene regulation by the protein kinase C (PKC) pathway in GT1-1 cells. … hikmah kisah nabi musa
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WebJan 1, 1998 · The Pa and Pb promoters of the Atlantic salmon (Salmo salar) GnRH gene were fused together or individually to the Escherichia coli lacZ gene, and their transcriptional activities were measured in ... Webactivator of the GnRH promoter through binding to four ATTA sites in the GnRH enhancer (E1) and proximal promoter (P), and able to compete … WebWith the development of mice in which the gene for green fluorescent protein has been put under the regulation of the GnRH promoter, it has been possible to identify GnRH neurons in hypothalamic tissue slices using fluorescence microscopy, to record from them intracellularly, 16 and to simultaneously measure GnRH release from the median ... ezs 6250